A low CD4 count means that HIV has weakened your immune system and may be making you ill. HIV treatment will strengthen your immune system and extend your life. While your CD4 count is low, you may also need to take antibiotics to prevent infections.

What causes low CD4?

Purpose of review: A severe decrease of CD4 T cells predisposes humans to opportunistic infections. In adults, HIV is certainly the most common cause of CD4 lymphocytopenia, but other causes, such as infections, autoimmune diseases, immunosuppressive therapy, lymphoma and idiopathic forms need to be considered.

How long does it take for CD4 to drop?

Time for CD4 count to drop to 200 (without ART). 25% people would take 1-2 years (fast progressors). 50% people would take 2-10 years. 25% people would take 10-15 years. Less than 1% people would still have a high CD4 count after 15 years.