Something changed when House and Cuddy kissed in the fifth season episode, “Joy.” Slowly, but surely, the show started to become more and more about whether or not these two would get together, culminating with a hook-up in one of Houses Vicodin-induced hallucinations in the season finale.

What episode do House and Cuddy sleep together?

Under My Skin In episode Under My Skin, Cuddy helps House detox from Vicodin; and the two sleep together.

Do House and Cuddy actually get together?

After a tumultuous stab at a mature relationship in Season 7, Cuddy dumps House after a cancer scare which House cannot bring himself to confront without the aid of his old friend Vicodin. Cuddy realizes that House is not and probably never will be ready for a real relationship and ends it.

Did House hallucinate his relationship with Cuddy?

House then has a flashback to the night (from the episode Under My Skin) before when he thought he told Cuddy that he needed her help with his addiction. The whole previous night was a complete hallucination, beginning from him telling Cuddy that he needed her to help him detox and her accompanying him home.